ELISA Phospho-RACGAP1 (Ser387) anti-

Quantity :100µL Clone Number: Aliases:CYK4 antibody; GAP antibody; Gap1 antibody; GTPase activating protein antibody; HsCYK-4 antibody; ID GAP antibody; KIAA1478 antibody; Male germ cell RacGap antibody; MgcRacGAP antibody; Protein CYK4 homolg antibody; Protein CYK4 homolog antibody; Rac GTPase activating protein 1 antibody; Rac GTPase-activating protein 1 antibody; RACGAP 1 antibody; Racgap1 antibody; RGAP1_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H0H5 Immunogen:Peptide sequence around phosphorylation site of serine 387 (R-I-S(p)-G-C) derived from GTPase Activating Protein. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: Component of the centralspindlin complex that serves as a microtubµLe-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells throµgh mechanisms other than regµLating Rac GTPase activity. Also involved in the regµLation of growth-related processes in adipocytes and myoblasts. May be involved in regµLating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Doki N, et al. (2009)Cancer Sci 100, 1675-9. Minoshima Y, et al. (2003)Dev Cell 4, 549-60. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RACGAP1 Research Areas:Cell biology;Signal transduction